Table 1 Sequences of anti-aggregation signal tested in this study
From: Engineered NLS-chimera downregulates expression of aggregation-prone endogenous FUS
Signal | Sequence |
|---|---|
FUS PY-NLS | GGRGGGDRGGFGPGKMDSRGEHRQDRRERPY |
hnRNPA1 PY-NLS | FGNYNNQS SNFGPMKGGN FGGRSSGPY |
M9M | GGSYNDFGNYNNQSSNFGPMKGGNFGGRFEPYANPTKR |
SV40 cNLS | PKKKRKV |
TDP-43 cNLS | KDNKRKMDETDASSAVKVKRAVQK |
IBB | NENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSF |
Rev NLS | RQARRNRRRRWRERQRQ |
cJun NLS | RKRKL |
