Fig. 6: Ribosome profiling in Mettl1^KO1 testes.

a Metagene plot for ribosome footprints around start codons. The 5′ ends of 29 nt reads are depicted. Pearson’s correlation coefficients (r), ribosome footprints (b), and RNA-Seq reads (c) on each ORF. The color scales for r are represented. d Ribosomal occupancy analysis across A-site codons in the Mettl1-KO testis. Source data is provided as a Source Data file. e Ribosome occupancy analysis for the codons decoded by the indicated tRNA groups (Group1: n = 15, Group2: n = 8, Group3: n = 22). Central bands, upper and lower edges of box plots represent median, first and third quartiles, respectively. Upper and lower whiskers represent maximum, and minimum values. f Metagene plot for ribosome occupancy around CCA codons. The positions of paused and collided ribosomes are highlighted by arrows. g Differences in ribosome occupancy changes on A-site codons in Mettl1-KO testes between all analyzed genes and genes that are essential for fertility (Supplementary Table S1).