Table 1 Semen analysis in Cep112+/+ and Cep112−/− male mice by CASA
Adult male mice | P value | ||
|---|---|---|---|
Cep112+/+ | Cep112−/− | ||
Semen parameters | |||
Sperm concentration (106/ml)a | 32.17 ± 4.42 | 6.14 ± 1.69 | 0.0007 |
Motility (%)b | 74.23 ± 3.50 | 4.50 ± 0.54 | <0.0001 |
Progressive motility (%)b | 71.51 ± 4.13 | 2.01 ± 0.94 | <0.0001 |
Sperm locomotion parameters | |||
Curvilinear velocity (VCL) (μm/s)b | 91.89 ± 7.59 | 7.80 ± 2.23 | <0.0001 |
Straight-line velocity (VSL) (μm/s)b | 41.86 ± 6.26 | 1.16 ± 0.23 | 0.0004 |
Average path velocity (VAP) (μm/s)b | 58.05 ± 2.18 | 3.00 ± 0.51 | <0.0001 |
Amplitude of lateral head displacement (ALH) (μm)b | 1.28 ± 0.22 | 0.18 ± 0.04 | 0.0010 |
Linearity (LIN)b | 0.45 ± 0.03 | 0.15 ± 0.02 | 0.0001 |
Wobble (WOB, =VAP/VCL)b | 0.63 ± 0.03 | 0.40 ± 0.07 | 0.0064 |
Straightness (STR, =VSL/VAP)b | 0.72 ± 0.08 | 0.38 ± 0.02 | 0.0020 |
Beat-cross frequency (BCF) (Hz)b | 7.13 ± 0.67 | 0.43 ± 0.06 | <0.0001 |