Fig. 2: Isomer-specific identification of mammalian brain gangliosides by LC-CID-MS/MS. | Nature Communications

Fig. 2: Isomer-specific identification of mammalian brain gangliosides by LC-CID-MS/MS.

From: Deciphering mouse brain spatial diversity via glyco-lipidomic mapping

Fig. 2

a, b Representative EICs and CID-MS/MS spectra of GD1a 36:1;O2 and GD1b 36:1;O2 from porcine and mouse brains, respectively. c Representative EIC of GQ1c 36:1;O2 with 2 O-acetylation from porcine and mouse brain. d CID-MS/MS spectra of GQ1c 36:1;O2 with 2 O-acetylation from mouse brain were shown. Diagnostic ions were highlighted with red asterisks. Monosaccharide legend: blue circle-Glucose, yellow circle-Galactose, Yellow square-N-acetylgalactosamine, Purple diamond-N-acetylneuraminic acid, Red triangle-Fucose. The ceramide tail was indicated by ‘Cer’. Some elements in this figure were created with BioRender.com, released under a Creative Commons Attribution 4.0 International license, https://creativecommons.org/licenses/by/4.0/.

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