Fig. 5: The UPRmt induced by ASI cco-1 KD is mediated by Dopamine and negatively regulated by GABA.
From: ASI-RIM neuronal axis regulates systemic mitochondrial stress response via TGF-β signaling cascade
a Representative fluorescence photomicrographs of hsp-6p::gfp in wild-type, cat-2, tbh-1, tph-1, unc-17, eat-4, tdc-1 and unc-25 animals in gpa-4p::cco-1HP background. b Fluorescence intensities of hsp-6p::gfp in animals shown in (a) were quantified using ImageJ. n = 30 worms. c Representative fluorescence photomicrographs of hsp-6p::gfp in wild-type, dop-1, dop-2, dop-3 and dop-4 in gpa-4p::cco-1HP background. d Fluorescence intensities of hsp-6p::gfp in animals shown in (c) were quantified using ImageJ. n = 30 worms. e Representative fluorescence photomicrographs of hsp-6p::gfp in wild-type, unc-47, unc-30, unc-49, lgc-35, exp-1, gbb-1 and gbb-2 animals in gpa-4p::cco-1HP background. f Fluorescence intensities of hsp-6p::gfp in animals shown in (e) were quantified using ImageJ. n = 30 worms. p values were annotated via ordinary one-way ANOVA in (b), (d) and (f). Error bars, SEM. Scale bar, 100 μm. Source data are provided as a Source Data file. See also Supplementary Fig. 5.
