Fig. 5: Two hOGG1 molecules binding to a single NCP-8-oxodGuo-137. | Nature Communications

Fig. 5: Two hOGG1 molecules binding to a single NCP-8-oxodGuo-137.

From: Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles

Fig. 5: Two hOGG1 molecules binding to a single NCP-8-oxodGuo-137.

a Illustration of representative 2D classification. b Crude map depicting the binding of hOGG1K249Q in conjunction with NCP-8-oxodGuo-137 at a ratio of 2:1, obtained from the same data collection as presented in Fig. 2. Orange represents hOGG1K249Q bound on 8-oxodGuo-137 (SHL 6.0), Pink corresponds to hOGG1K249Q bound at SHL −2.0. NCP, nucleosome core particle. SHL, superhelical location.

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