Table 1 Dissociation constant (Kd) of hOGG1K249Q with various substrates
From: Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles
Substrate | Kd (μM) | Substrate | Kd (μM) |
|---|---|---|---|
dsDNA | 1.31 ± 0.20 | NCP | 1.70 ± 0.03 |
dsDNA-8-oxodGuo-73 | 0.24 ± 0.01 | NCP-8-oxodGuo-73 | 1.54 ± 0.03 |
dsDNA-8-oxodGuo-89 | 0.30 ± 0.01 | NCP-8-oxodGuo-89 | 2.03 ± 0.07 |
dsDNA-8-oxodGuo-137 | 0.42 ± 0.02 | NCP-8-oxodGuo-137 | 1.36 ± 0.04 |
