Fig. 5: Experimental studies and proposed mechanism for carbon-atom insertion of indoles with fluoroalkyl carbenes.
From: Halogencarbene-free Ciamician-Dennstedt single-atom skeletal editing
a Identification of the reaction intermediates. b Experiments to probe the source of the hydrogen atom incorporated in quinoline-3-carboxaldehyde. c Experiment to validate the process of imine-enamine tautomerization. d Probing source of oxygen atom incorporated into quinoline-3-carboxaldehyde. e Proposed reaction pathways for one-carbon insertion of indoles with fluoroalkyl carbenes.
