Table 1 Cohort characteristics

From: Bidirectional relationship between epigenetic age and stroke, dementia, and late-life depression

Variable

Overall (n = 4018)

Prevalent brain health events (n = 806)

Incident Brain health events (n = 261)

Demographics

Age (mean (SD))

69.9 (9.6)

75.2 (10.1)

73.0 (9.3)

Male gender

1669 (41.5)

334 (41.4)

115 (44.1)

Race

White

3013 (75.0)

572 (71.0)

204 (78.2)

Black

674 (16.8)

170 (21.1)

40 (15.3)

Hispanic

207 (5.2)

42 (5.2)

12 (4.6)

Other

122 (3.0)

22 (2.7)

5 (1.9)

Cardiovascular Risk factors

Prevalent hypertension

2559 (63.7)

604 (74.9)

186 (71.3)

Prevalent diabetes

1151 (28.6)

306 (38.0)

85 (32.6)

BMI (mean (SD))

28.92 (6.30)

28.4 (6.4)

28.9 (6.1)

Smoking

Past

1776 (44.2)

399 (49.5)

118 (45.2)

Never

1764 (43.9)

307 (38.1)

113 (43.3)

Current

455 (11.3)

95 (11.8)

29 (11.1)

Prevalent heart condition*

1098 (27.3)

356 (44.2)

80 (30.7)

  1. *Heart conditions include: heart attack, coronary artery disease, angina, congestive heart failure
  2. Note: The terms prevalent, respectively incident, refer to conditions having occurred before, respectively, after, the epigenetic age estimation performed during the 2016 wave.