Fig. 7: Anti-tumor therapeutic effect in vivo of C5T-Pc and C5T-Pco NPs. | Nature Communications

Fig. 7: Anti-tumor therapeutic effect in vivo of C5T-Pc and C5T-Pco NPs.

From: Aggregation control of anionic pentamethine cyanine enabling excitation wavelength selective NIR-II fluorescence imaging-guided photodynamic therapy

Fig. 7: Anti-tumor therapeutic effect in vivo of C5T-Pc and C5T-Pco NPs.

a Schematic illustration of PDT process of C5T-Pco NPs; Body weight curves (b) and tumor growth curves (c) of mice in the different groups; Average tumor weight (d) and photograph (e) of tumor tissues of mice in the different groups (G1 group represents for mice intravenously injected with PBS (100 μL), G2 group represents for mice with 760 nm laser irradiation, G3, G4, and G5 groups represent for mice intravenously injected with ICG, C5T-Pc NPs, C5T-Pco NPs ([Cyanine] = 100 μg mL−1, 100 μL) without laser irradiation, respectively, G6 group represents for mice intravenously injected with ICG with 808 nm laser irradiation, G7 and G8 groups represent for mice intravenously injected with C5T-Pc and C5T-Pco NPs with 760 nm laser irradiation, respectively). The results are represented of n = 5 independent experiments. All graphs are represented as means ± s.d. Statistical differences were analyzed by one-way ANOVA with Bonferroni Test.

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