Fig. 3: iPSYCH2012 results.
From: Leveraging haplotype information in heritability estimation and polygenic prediction
Heritability estimation and polygenic prediction in the iPSYCH2012 case-cohort. The left plot shows the SNP heritability estimates on the liability scale using the different GRMs across the three disorders, while the right plot shows Nagelkerke’s pseudo R2 between the leave-one-out cross-validated polygenic predictions (cvBLUPs) and the binary outcomes. MDD: N = 45,848, REC: N = 32,968, and SCZ: N = 29,205. Data in the left plot are represented as heritability estimates  ±1.96 × SE. Data in the right plot are represented as \({R}_{N}^{2}\) values and the interval bars span the 2.5% and 97.5% percentiles from non-parametric bootstrapping of 1000 iterations. Source data are provided as a Source Data file.
