Fig. 1: Overall structures of Gs-coupled zGPR4 under pH 6.5 and 8.5. | Nature Communications

Fig. 1: Overall structures of Gs-coupled zGPR4 under pH 6.5 and 8.5.

From: Cryo-EM structure of an activated GPR4–Gs signaling complex

Fig. 1: Overall structures of Gs-coupled zGPR4 under pH 6.5 and 8.5.

a–d Cryo-EM maps showing the disk-shaped micelle (left) and cartoon representation (right) of the zGPR4–Gs complexes under pH 6.5 (a, c) and pH 8.5 (b, d). e, f Superposition of the two structures at pH 6.5 and 8.5 on side view (e) or extracellular view (f). The disulfide bond is shown in stick.

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