Table 1 Comparison of the performance of the COFcap-2 tandem catalysis reactor and a previously reported homogeneous biocatalyst for asymmetric amination of prochiral ketones
From: COFcap2, a recyclable tandem catalysis reactor for nitrogen fixation and conversion to chiral amines
Entry | Product | eep (%) | Productivity (this work, μM·h−1) | Productivity (homogeneous biocatalyst13, μM·h−1) |
|---|---|---|---|---|
1 |
| >99 (R) | 62 | 54 |
2 |
| >99 (R) | 43 | 34 |
3 |
| >99 (R) | 27 | n.da |
4 |
| >99 (R) | 25 | n.da |
5 |
| >99 (R) | 32 | -b |
6 |
| >99 (R) | 20 | 14 |
7 |
| >99 (R) | 54 | 53 |
8 |
| >99 (R) | 38 | 35 |
9 |
| >99 (R) | 35 | -b |
10 |
| >99 (R) | 21 | -b |
11 |
| >99 (R) | 30 | -b |
