Fig. 7: Free energy profile for the CPA catalyzed enantioselective trifunctionalization with α-bromo Rh-carbenes.
From: Asymmetric multi-component trifunctionalization reactions with α-Halo Rh-carbenes
Both the non-bromine products pathway (A, in red) and bromine products pathway (B, in blue) are explored. The former pathway was proved to be more favored.
