Table 1 Baseline Demographic and Clinical Characteristics

Age at Enrollment (years) - Median [range]

42.0 [24.0, 78.0]

Sex: Female – n (%)

1 (7%)

 White

12 (86%)

 Asian

1 (7%)

 Unknown/Not Reported

1 (7%)

Recipient Eye Characteristics

N = 14

 Epithelial Defect– n (%)

4 (29%)

 Epithelial Defect Surface Area (mm²), in 4 eyes with defect - All epithelial defects

0.3, 6.5, 16.0, 21.6

 Cornea Surface Staining (NEI Grade Scale of 0 to 15)^a - Median [range]

15.0 [10.0, 15.0]

 Neovascular Area (% of Total Area)^b - Median [range]

7.5 [0.5, 24.2]

 Clock Hours of Limbal Involvement - Median [range]

12.0 [8.0, 12.0]

 Central 5 mm involved – n (%)

12 (86%)

 OSDI Score (Scale of 0 to 100) - Median [range]

40.6 [6.8, 100.0]

 SANDE Score (Scale of 0 to 100)^c - Median [range]

35.4 [6.5, 82.0]

 Chemical burn

9 (64%)

 Thermal burn

2 (14%)

 Other^e

3 (21%)

 Time from Injury to CALEC (years) - Median [range]

2 (0, 32)

 Number of Reconstructive Surgeries Prior to CALEC - Median [range]

0.5 (0.0, 4.0)

 2

2 (14%)

 3

6 (43%)

 4

6 (43%)

 20/40 to 20/100

3 (21%)

 20/300 to 20/400

2 (14%)

 Hand motion or count fingers

9 (64%)

 Median [range]

14.5 [8.0, 24.0]

Positive Culture Growth from Conjunctival Swab – n (%)^d

10 (77%)