Fig. 7: Macrophage AMPK-SUCLA2-IL-1β pathway of adipose tissue is involved in human obesity. | Nature Communications

Fig. 7: Macrophage AMPK-SUCLA2-IL-1β pathway of adipose tissue is involved in human obesity.

From: Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK

Fig. 7

a Immunofluorescent staining of CD68, pT172-AMPK, pS60-SUCLA2 and IL-1β in the subcutaneous adipose tissue from lean (BMI = 21.5), overweight (BMI = 25.7) or obese (BMI = 32.0) subjects, representative data are shown from one of the three independent experiments. b Model of how macrophage AMPK responds to glutaminolysis and regulates glutaminolysis-coupled IL-1β expression, and this image was created in BioRender. Zang, Y. (2025) https://BioRender.com/e16k510.

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