Fig. 4: Active site interactions in the CG, TG and TT complexes.
From: Structural basis of error-prone DNA synthesis by DNA polymerase θ
a Interactions at the active site in the CG complex (blue) are nearly superimposable with those in LcPol θ (salmon) and Pol I (yellow). O- and Oα-helices are shown as semi-transparent cartoon. b–d Interactions at the active site in the CG, TG and TT complexes. Critical contacts between Pol θ, the nascent base pair, and Mg2+ are shown as dashed lines. The finger and palm domains are colored in lightblue and lightpink, respectively.
