Fig. 2: Orpheus performance for TAILORx risk stratification.
From: Multimodal histopathologic models stratify hormone receptor-positive early breast cancer
a–c The whole-slide image (WSI)-based model reliably identifies high-risk disease (RS > 25) as defined by TAILORx across the MSK-BRCA (n = 1029), IEO-BRCA (n = 452), and MDX-BRCA (n = 572) test cohorts. d The multimodal model outperforms the WSI- and text-based unimodal models. Error bars by 1000-fold bootstrapping. e, f The multimodal model outperforms a clinicogenomic nomogram in identifying high-risk diseases. g Calibration plot and h predicted score frequencies. All results are shown for test sets.
