Table 1 Clinicopathologic characteristics of EG and YG patients

From: Comprehensive characterization of early-onset lung cancer, in Chinese young adults

 

EG (n = 206)

YG (n = 215)

P value

Median age

67 (60–79)

36 (20–40)

 
 

N

%

N

%

 

Sex

  Male

85

41.3

70

32.6

0.06

  Female

121

58.7

145

67.4

 

Smoking history

  Yes

48

23.3

30

14

0.01*

  No

158

76.7

185

86

 

Family History

  Yes

15

7.3

9

4.2

0.17

  No

191

92.7

206

95.8

 

Symptoms at diagnosis

  Yes

81

39.4

38

17.7

0.00****

  No

125

60.7

177

82.3

 

Stagea

  IA1,2,3 + B

133

64.5

183

85.1

 

  IIA + B

15

7.3

18

8.4

0.00****

  IIIA + B + C

28

13.6

4

1.9

 

  IVA + B

30

14.6

10

4.6

 

Tumor size

  T1

148

71.8

193

89.8

 

  T2

30

14.6

12

5.6

0.00****

  T3

18

8.7

4

1.9

 

  T4

10

4.9

6

2.7

 

Lymphatic metastasis

  Yes

52

25.2

18

8.4

0.00***

  No

154

74.8

197

91.6

 

Distant metastasis

  Yes

30

14.6

15

7

0.02*

  No

176

85.4

200

93

 

Risk gradingb

  Grade 1

86

41.8

113

52.6

 

  Grade 2

50

24.3

66

30.7

0.00****

  Grade 3

30

14.6

29

13.5

 

  Undefinablec

40

19.4

7

3.3

 
  1. The P values of Table 1 were analyzed using the two-sided chi-square test. *, P < 0.05; ***, P < 0.001; ****, P < 0.0001
  2. aAccording to the latest IASLC 9th edition tumor staging.
  3. bPathological subtyping is graded according to the IASLC grading system.
  4. cFor some advanced-stage patients who did not undergo surgery, it was not possible to obtain accurate pathological morphological data, which was treated as undefinable.
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