Fig. 4: Performance of LOF O/E trained on different UKB cohorts.
From: Diverse ancestral representation improves genetic intolerance metrics
AUC-ROC scores illustrating the ability of LOF O/E to predict five different gene lists. Each score represents a version of the score trained on the UKB cohorts composed of different ancestries. AFR African, ASJ Ashkenazi Jewish, EAS East Asian, SAS South Asian, NFE non-Finnish European, DEE developmental and epileptic encephalopathy, DD developmental delay, ASD autism spectrum disorder.
