Fig. 8: Simulation images for equal-component ternary TF mixtures.
From: Selective phase separation of transcription factors is driven by orthogonal molecular grammar
a EWS-SP1-TAF15, b FUS-SP2-TAF15, c SP1-SP2-TAF15, d FUS-HNF1A-TAF15, e HNF1A-SP1-TAF15, f HNF1A-SP1-SP2. All simulations were run with a total amino acid concentration of 80,000 μM. The end frame of 3 μs of simulation is displayed as a representative state. A segment is not displayed to reveal the internal droplet structure. FUS molecules are coloured in yellow, EWS molecules are coloured in orange, SP1 molecules are coloured in purple, SP2 molecules are coloured in light purple, HNF1A molecules are coloured in red, and TAF15 molecules are coloured in green. Corresponding radial density profiles can be found in Supplementary Fig. 33.
