Fig. 3: Reduced growth rates of aneuploid C. albicans strains.

a Growth curves in liquid YPD at 30 °C during a 21-hour window are shown for 10 aneuploid strains (in blue), the diploid control (in dark grey), and tetraploid control (in light grey). OD₆₀₀ measurements are shown in 15-minute intervals with standard deviations. Data are plotted as the mean with error bars indicating the standard deviation. N = 4. b The average doubling time during exponential growth was calculated for all strains and plotted as the mean and interquartile ranges (IQR) with whiskers extending to 1.5 × IQR. Data points extending beyond 1.5 × IQR are plotted individually. Strains are ordered from left to right by the amount of excess DNA in the aneuploid strain. N = 4. Significance was determined by two-sided Student’s t-test relative to the diploid strain without multiple comparison adjustments. * denotes p < 0.05. ** denotes p < 0.01. *** denotes p < 0.001.