Table 4 Summary of the results of the task-based brain activity, metabolite, and behavior results
From: Relationships between brain activity, tryptophan-related gut metabolites, and autism symptomatology
ROI/Stimuli (vs. rest) | Metabolite/Pathway (DV) | Behavior (DV) |
|---|---|---|
R MI/ Disgusting Foods* | Indolelactate (-)*/Indole | ADOS Total (-)* |
Indolelactate (-)*/Indole | ADOS RRB (-)* | |
R MCC/Non-Emo Faces* | C-glycosyltryptophan (+)*/5-HT | DPSS-R Sensitivity (+)* |
Tryptophan betaine (-)/Other | – | |
dmPFC/aMCC/Object Touch | Indole-3-carboxylate (+)/Indole | – |
– | FISH Total (+) | |
L PI/Social Touch | Indole-3-carboxylate (-)/Indole | – |
L dAI/Disgusted Faces | Kynurenate (+)/Kynurenine | – |
– | ADOS RRB (-) | |
R IFGop/All Faces | Anthranilate (+)/Indole | – |
L IFGop/Emo Faces | Anthranilate (+)/Indole | – |
R MCC/All Faces | Tryptophan betaine (-)/Other | |
R S1/Object Touch | Indole-3-carboxylate (+)/Indole | – |
R MCC/Hand Actions | N-acetyltryptophan (+)/Other | |
L vAI/Disgusting Foods | – | ADI-R RRB (-) |
pACC/Disgusted Faces | – | SEQ EP (+) |
R FFA/Disgusted Faces | – | ADI-R RRB (+) |
R MCC/All Faces + Hands | – | Conners Probability (-) |
R MCC/Emo Faces | – | Conners Probability (-) |
– | 5-hydroxypicolinic acid/ Kynurenine | DPSS-R Propensity (+) |
– | Tryptophol/ Other | SEQ- Non-social (+) |
– | Tryptophol/ Other | SEQ- Vestibular/ Proprioception (+) |
– | 3-indoxyl sulfate/ Indole | ADI-R RSI (+) |
– | Indolepropionate/ Indole | AQC- 2 Factor (+) |
– | Anthranilate/ Indole | ASWS Total (+) |
