Fig. 4: Asymmetric synthesis of P-chiral benzophospholes.
Reaction conditions: 1 (0.20 mmol), Pd(OAc)2 (5 mol% Pd), (R)-DM-segphos (10 mol%), CsOPiv (0.40 mmol), and m-xylene (1.0 mL) at 140 °C for 12 h. Isolated yield. The % ee was determined by HPLC on a chiral stationary phase column.
