Fig. 2: Cryo-EM structures of MtUvrA2-DNA, MtUvrA2UvrB1-DNA* and MtUvrA2UvrB2-DNA* complexes. | Nature Communications

Fig. 2: Cryo-EM structures of MtUvrA2-DNA, MtUvrA2UvrB1-DNA* and MtUvrA2UvrB2-DNA* complexes.

From: Mechanistic understanding of UvrA damage detection and lesion hand-off to UvrB in Nucleotide Excision Repair

Fig. 2: Cryo-EM structures of MtUvrA2-DNA, MtUvrA2UvrB1-DNA* and MtUvrA2UvrB2-DNA* complexes.

a The indicated cryo-EM reconstructions are color coded and labeled according to the models shown in b; in the MtUvrA2-DNA and MtUvrA2UvrB1-DNA* reconstructions, the yellow and the red arrowhead points out the lack of signal corresponding to a 7-nt long segment of one DNA strand, and to one MtUvrA protomer ID, respectively. b Cartoon representation of the MtUvrA2-DNA, MtUvrA2UvrB1-DNA* and MtUvrA2UvrB2-DNA* models in two orientations; in the side views it is possible to appreciate the initial bending of the DNA in MtUvrA2-DNA and MtUvrA2UvrB1-DNA* and the final position in the groove of MtUvrA2UvrB2-DNA* structure. The unmodeled DNA strand segment on MtUvrA2-DNA is represented with a dashed line.

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