Fig. 4: Novel site prediction and validation with Library-ChIP confirms role of accessory bases. | Nature Communications

Fig. 4: Novel site prediction and validation with Library-ChIP confirms role of accessory bases.

From: Predictive biophysical neural network modeling of a compendium of in vivo transcription factor DNA binding profiles for Escherichia coli

Fig. 4

A Novel site designs for PdhR, AllR, and GlnG. For each TF, the top singleton binding site was selected as a reference (sequence logo) and all combination of accessory bases (pink shading) were generated and used as input to the corresponding BoltzNet model. B–D Scatter plots of BoltzNet predictions vs Library-ChIP enrichment.

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