Fig. 7: Epigraph provides rapid and durable antibody responses in swine.
From: Epitope-optimized vaccine elicits enduring immunity against swine influenza A virus
A Schematic representation of immunization and sampling schedule for longitudinal study. HI antibody responses over the full six-month sampling duration against representative IAV-S from (B, C) α clade (1A.1), (D, E) β clade (1A.2), (F, G) γ clade (1A.3.3.3), (H) δ1 clade (1B.2.2), and (I, J) npdm clade (1A.3.3.2). HI antibody responses against (K, L) human H1N1pdm09 IAV and (M) a representative avian H1 (1A.1-like) IAV. Data in (B–M) are presented as the mean ± SEM (n = 5 pigs per group per timepoint; one-way ANOVA with Tukey’s multiple comparison). Dashed lines indicate a 50% protective titer (≥1:40; 5.32 log2). A table of the statistical analysis between groups at each timepoint is available in Supplementary Fig. 4. Created in BioRender. Madapong, A. (2025) https://BioRender.com/p8fljxn.
