Fig. 9: Structural conservation of RNA triphosphatase. | Nature Communications

Fig. 9: Structural conservation of RNA triphosphatase.

From: RNA triphosphatase-mediated mRNA capping is essential for maintaining transcript homeostasis and the survival of Toxoplasma gondii

Fig. 9

A Predicted structure of TgCet (361–729aa) using Collabfold. B The structure contains a ten-stranded anti-parallel β-barrel with three α-helices surrounding the active-site tunnel. C The predicted structure of TgCet in green was superimposed on S. cerevisiae Cet1 colored in yellow (1D8H). D Conservation of active site residues of ScCet1, TgCet, TcCet1, and hTTP. E The predicted structure of TgCet in green was superimposed on T. cruzi Cet1 colored in blue (6L7W). F The predicted structure of TgCet in green was superimposed on human thiamine triphosphates, colored in red (3TVL).

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