Table 3 Solicited respiratory adverse events
Systemic adverse events | Uninfected | Previously infected | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HuAd 1 × 105 n = 3 | HuAd 1 × 106 n = 3 | HuAd 1 × 107 n = 3 | HuAd 3 × 107 n = 3 | ChAd 1 × 105 n = 3 | ChAd 1 × 106 n = 3 | ChAd 1 × 107 n = 3 | ChAd 3 × 107 n = 3 | ChAd 1 × 108 n = 3 | ChAd 3 × 107 n = 3 | ChAd 6 × 107 n = 6 | ||||||||||||
Grade | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 |
Cough | 0 | 0 | 0 | 0 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 0 | 4 | 0 | 0 | 0 | 2 | 0 |
Shortness of breath | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased respiratory secretions/rhinorrhea | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Respiratory infection | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 2 | 0 |
Non-cardiac chest pain | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sore throat | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Nasal bleeding | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lymphadenopathy (cervical) | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Total respiratory adverse events | 4 | 0 | 2 | 0 | 4 | 0 | 6 | 0 | 2 | 1 | 1 | 0 | 5 | 0 | 4 | 0 | 7 | 2 | 1 | 0 | 4 | 0 |
