Fig. 2: FABP7 increased CD16, CD80 and IL-1β in monocytes. | Nature Communications

Fig. 2: FABP7 increased CD16, CD80 and IL-1β in monocytes.

From: FABP7 is increased in progressive multiple sclerosis and induces a pro-inflammatory phenotype in monocytes through a glycolytic switch

Fig. 2: FABP7 increased CD16, CD80 and IL-1β in monocytes.

Monocytes were treated in vitro with FABP7 or FABP4 for 48 h. Flow cytometry was performed, and data is represented as (a) bars (mean ± SD, n = 12) indicating percentage of cell population gated from CD14+ cells from HCs and (b) zebra plot showing expression of IL-1β based on FMO. One-way ANOVA was performed following correction with Dunnett’s multiple comparison test for (a). c Bars (mean ± SD, n = 9) showing cell populations gated from CD14+ cells in HCs and SPMS. Two-way ANOVA was performed following correction with Šidák multiple comparison test. d zebra plot showing expression of IL-1β. P-values are shown above the comparisons. FMO  Fluorescent minus one.

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