Fig. 2: Relative sEVs and dsDNA levels in the mouse model with RIM. | Nature Communications

Fig. 2: Relative sEVs and dsDNA levels in the mouse model with RIM.

From: Nanostructured organic sheets sequestering small extracellular vesicles and reactive species to protect against radiation-induced mucositis

Fig. 2: Relative sEVs and dsDNA levels in the mouse model with RIM.

a Representative images of anti-IL-6 or anti-CitH3 immunostaining in the nasal mucosa from mice subjected to different treatments. Scale bars in IL-6 images: 100 µm; CitH3: 50 µm. b Quantification of the percentage of IL-6 positive area and CitH3 positive area in the immunostaining images. c The relative expression levels of IL-1β, IL-6, IL-8, and TNF-α in the nasal mucosa of experimental mice. Data represent the mean ± S.D. (n = 6 mice). Statistical significances were assessed by one-way ANOVA (b, c), and multiple comparisons post hoc tests were performed via the Prism recommendation (Tukey or Dunnett) method. Abbreviations: NETs: neutrophil extracellular traps. Source data are provided as a Source Data file.

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