Fig. 2: Comparison of MeiHMM with trio analysis. | Nature Communications

Fig. 2: Comparison of MeiHMM with trio analysis.

From: Inferring chromosome segregation error stage and crossover in trisomic disorders with application to Down syndrome

Fig. 2: Comparison of MeiHMM with trio analysis.

A Comparison of MeiHMM with trio analysis. B MeiHMM identified 87 of the 95 crossovers at similar positions and crossovers very close to the centromere leads to incorrect classifications. C Comparison of the minimum block size of correctly and incorrectly classified cases. D Frequencies of MI, MII, and mitotic errors identified by MeiHMM in 764 DS cases. E, F Distribution of the crossovers on chr 21 in (E) MI and (F) MII errors. MI meiosis I, MII meiosis II, DS Down syndrome, WGS whole genome sequencing. Source data are provided as a Source Data file.

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