Fig. 7: Effect of UCNP@CR in wound biofilm infection treatment.

a Schematic diagram of ultrasound assisted photodynamic treatment for fungal biofilm infection; b Pathological section of wound biofilm infection with H&E and PAS staining (Arrow pointing towards the biofilm); c, d Representative photographs of wound healing status of mice from day 1 to day 11 and corresponding simulated in vivo wound closure traces; e Relative wound recovery area of different groups (US: ultrasound, 1 MHz, 0.5 W cm⁻², 60 s; L: light, 980 nm, 0.5 W cm⁻², 15 min; mean ± SD from n = 5 mice); f Statistics of Candida albicans quantity in wound area (mean ± SD from n = 5 mice). In e, f statistical tests used for data analysis are one-way ANOVA and two-way ANOVA with a Tukey post-hoc test, respectively. In b the experiments were repeated independently three times with similar results.