Fig. 1: Enhanced dsRNA stability and uptake in S. frugiperda by dsRNA@ZIF-8@PDA NPs. | Nature Communications

Fig. 1: Enhanced dsRNA stability and uptake in S. frugiperda by dsRNA@ZIF-8@PDA NPs.

From: Increased and synergistic RNAi delivery using MOF polydopamine nanoparticles for biopesticide applications

Fig. 1

a, b SEM images of dsGFP@ZIF-8 and dsGFP@ZIF-8@PDA. c–e TEM images of dsGFP, dsGFP@ZIF-8 and dsGFP@ZIF-8@PDA. f Dimensional probability distribution plot of dsGFP@ZIF-8@PDA fitted by Gaussian model. g Zeta potential of ZIF-8, dsGFP@ZIF-8 and dsGFP@ZIF-8@PDA. (Mean ± SD; n  =  6 technical replicates, F2,17 = 642.73, P < 0.001). Statistical differences were calculated using one-way analysis of variance (ANOVA) with Tukey’s HSD test. Exact P-values are reported in the source data. h–j ITC titration of Zn2+ (0.84 mM) into 2-mIm (10 mM) solution and dsGFP (0.5 mM) into 2-mIm (5 mM) solution. k The fluorescent intensity distribution of S. frugiperda gut and fat body tissues after feeding maize leaves smeared with Cy3-dsGFP and Cy3-dsGFP@ZIF-8@PDA, respectively (n = 4 replicates). l The fluorescent intensity distribution of Sf9 cell incubated with Cy3-dsGFP and Cy3-dsGFP@ZIF-8@PDA, respectively. Relevant source data are provided as a source data file (n = 5 replicates).

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