Fig. 6: Effect of NCU and GA hydrogel treatment on rat I/R model.
From: Plant-derived hydrogel and photosynthetic nano-units for myocardial infarction therapy
a Flow chart of animal experimental design. b Lighting and ECG recording during ischemic stage. c ECG confirmed successful ligation and reperfusion. d Echocardiography measurement of cardiac function (2 h post-operation). e Comparison of LVEF among groups (post 2 h, n = 6). f Comparison of LVFS among groups (post 2 h, n = 6). g TTC staining indicating NCUs reduced ischemic infarction. h Quantitative analysis of (g) (n = 5). i LVEF among groups at day 7 (n = 6). Data are mean ± SD, P < 0.05 was considered statistically significant, and P-values are indicated on the graphs, Unpaired t test (two-tailed) for (h), one-way ANOVA with Tukey’s multiple comparisons test for (e, f, and i). The cartoon rats in (a, g) and the cardiac section in (d) were created with BioRender.com. Echo, echocardiography; IPC, intrapericardial; PVC, premature ventricular contraction.
