Fig. 6: Full-length and truncated coiled-coil version of the dsDNA bound S. cerevisiae MR complex and details of MR-DNA interactions during MD simulation. | Nature Communications

Fig. 6: Full-length and truncated coiled-coil version of the dsDNA bound S. cerevisiae MR complex and details of MR-DNA interactions during MD simulation.

From: Structure guided functional analysis of the S. cerevisiae Mre11 complex

Fig. 6: Full-length and truncated coiled-coil version of the dsDNA bound S. cerevisiae MR complex and details of MR-DNA interactions during MD simulation.

A, B The topology of the full-length (panel A) and coiled-coil truncated (B) DNA bound MR complex. C, D Details of amino acid K192, K196, K1181, D1128, and P168 side chain conformations before (C) and after (D) 30 ns of MD simulations. Salt bridges are shown as dashed lines. The side chain of P168 is shown in space-filling representation. Lysine residues involved in hydrogen bond formation are shown by red arrows.

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