Fig. 4: Phylogenetic and functional analysis of TriDTC homologs. | Nature Communications

Fig. 4: Phylogenetic and functional analysis of TriDTC homologs.

From: Noncanonical terpene cyclases for the biosynthesis of diterpenoids regulating chlamydospore formation in plant-associated Trichoderma

Fig. 4: Phylogenetic and functional analysis of TriDTC homologs.

a Neighbor-joining tree of TCs including: TriDTCs (red), canonical type I TCs from bacteria (purple), fungi (brown), plants (green), and octocorals (yellow), as well as noncanonical TCs (pink). b Expanded view of the TriDTC clade with characterized enzymes labeled. The functional members are highlighted in red. c In vivo enzymatic production of compounds 1 and 2 by TriDTCs expressed in E. coli BL21 system. d Production of compounds 1 and 2 by TriDTCs expressed in A. oryzae NSAR1 system. Productions are represented as mean values ± SD (n = 3 biological replicates). Source data are provided as a Source Data file.

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