Fig. 5: Six sQTLs colocalize with OA GWAS signals. | Nature Communications

Fig. 5: Six sQTLs colocalize with OA GWAS signals.

From: Response splicing quantitative trait loci in primary human chondrocytes identify putative osteoarthritis risk genes

Fig. 5: Six sQTLs colocalize with OA GWAS signals.

a Total hip replacement (THR) GWAS signal colocalizes with an sQTL found in both conditions for PBRM1 associated with splice intron junction chr3:52658315–52662133. b THR GWAS signal colocalizes with an sQTL found in both conditions for GCAT associated with splice intron junction chr22:37808163–37809949. c Total joint replacement (TJR) GWAS signal colocalizes with an sQTL found in both PBS-treated chondrocytes for HMGN1 associated with splice intron junction chr21:39347292–39347379. d Finger OA GWAS signal colocalizes with an sQTL found in both conditions for RNF144B associated with splice intron junction chr6:18399699–18401957. e Knee OA GWAS signal colocalizes with an sQTL found in PBS-treated chondrocytes for WWP2 associated with splice intron junction chr16:69925484–69929448. f THR GWAS signal colocalizes with an sQTL found in PBS-treated for COLGALT2 associated with splice intron junction chr1:183978520–184037581.

Back to article page