Fig. 8: Genome-Wide Polygenic Scores (PGS) show significant associations across brain imaging modalities.
From: Polygenic architecture of brain structure and function, behaviors, and psychopathologies in children
Heat-map of genome-wide PGS (rows) showing significant loadings across canonical components for five brain-imaging modalities (columns): structural MRI (sMRI), diffusion MRI streamline count (dMRI-Count), diffusion MRI fractional anisotropy (dMRI-FA), resting-state fMRI (rsfMRI), and task-based N-Back fMRI. Colour scale –1 (blue) to + 1 (red). Only components with significant correlations are displayed. IDP imaging-derived phenotype, sMRI structural MRI, dMRI-Count, diffusion MRI streamline count, dMRI-FA diffusion MRI fractional anisotropy, rsfMRI resting-state functional MRI, PGS polygenic score.
