Fig. 7: The therapeutic efficacy of FAB@MN in rabbit ear HS models. | Nature Communications

Fig. 7: The therapeutic efficacy of FAB@MN in rabbit ear HS models.

From: 5-ALA photodynamic metabolite-powered zero-waste ferroptosis amplifier for enhanced hypertrophic scar therapy

Fig. 7: The therapeutic efficacy of FAB@MN in rabbit ear HS models.The alternative text for this image may have been generated using AI.

A Experimental timeline of animal studies. B Fluorescence imaging of ROS levels in rabbit ear HS models after different treatments, acquired using an In Vivo Imaging System (IVIS). C ROS staining of HS from different groups (Scale bar: 200 μm). D Representative photographs of the scars with four rounds of treatments (Scale bar: 5 mm). E Ultrasound images of scars after predetermined treatments (Scale bar: 2 mm). F H&E, G Masson, Sirius Red and GPX4 immunohistochemical staining of scar tissues after various treatments. H Scheme diagram of efficient anti-scarring efficacy of FAB@MN treatment. Experiments in (C), (F, G) were each performed thrice independently, yielding similar results each time. Source data are provided as a Source Data file. Some components of the schematic in (A) were created using BioRender. Wang, S. (2025) https://BioRender.com/7i8m28b.

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