Fig. 6: Shared microbes between the maternal microbiome and the neonatal gut microbiome. | Nature Communications

Fig. 6: Shared microbes between the maternal microbiome and the neonatal gut microbiome.

From: Vaginal Lactobacillus crispatus in early pregnancy associates with favorable gestational outcomes in a Japanese maternal-neonatal microbiome cohort

Fig. 6: Shared microbes between the maternal microbiome and the neonatal gut microbiome.The alt text for this image may have been generated using AI.

a, b Proportion and relative abundance of ASV types in the neonatal gut microbiome that were shared with the maternal vaginal or gut microbiome in vaginally delivered offspring (Vagina Day 0: n = 16, Day 1: n = 17, Day 4: n = 20, Month 1: n = 18; Gut Day 0: n = 16, Day 1: n = 17, Day 4: n = 19, Month 1: n = 17). c, d Proportion and relative abundance of ASV types in the neonatal gut microbiome that were shared with the maternal vaginal, gut, or skin microbiome in cesarean-section-delivered offspring (Vagina Day 0: n = 10, Day 1: n = 13, Day 4: n = 22, Month 1: n = 20; Gut Day 0: n = 8, Day 1: n = 12, Day 4: n = 22, Month 1: n = 20; Skin Day 0: n = 6, Day 1: n = 10, Day 4: n = 18, Month 1: n = 17). e Comparison of the proportion and relative abundance of ASV types shared with the maternal gut microbiome between the gut microbiomes of vaginally delivered (Day 0: n = 16, Day 1: n = 17, Day 4: n = 19, Month 1: n = 17) and cesarean-section-delivered offspring (Day 0: n = 8, Day 1: n = 12, Day 4: n = 22, Month 1: n = 20; Skin Day 0: n = 6, Day 1: n = 10, Day 4: n = 18, Month 1: n = 17). f Comparison of the proportion and relative abundance of ASV types shared with the maternal vaginal microbiome between the gut microbiomes of vaginally delivered (Day 0: n = 16, Day 1: n = 17, Day 4: n = 20, Month 1: n = 18) and cesarean-section-delivered offspring (Vagina Day 0: n = 10, Day 1: n = 13, Day 4: n = 22, 96Month 1: n = 20). Each p-value in all Figures is shown in Supplementary Table 7. Data are presented as means ± standard errors of the mean. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, Mann–Whitney U test (two-sided) for comparisons of two groups in panels (a), (b), (e), and (f). Kruskal–Wallis test followed by Dunn’s test (two-sided) for multiple comparisons in panels (c) and (d).

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