Table 2 Comparison of clinical characteristics between mothers with vaginal microbiome dominant with Lactobacillus vs. those with other genera

From: Vaginal Lactobacillus crispatus in early pregnancy associates with favorable gestational outcomes in a Japanese maternal-neonatal microbiome cohort

 

Lactobacillus

Other genera

p-value

Maternal general information

Number of mothers

29

10

 

Age at birth, years

36 (32.5–40.0)

34.5 (30.8–38.0)

0.2597

Childbirth history, yes/no

11/18

6/4

0.2819

Assisted reproductive technology, yes/no

14/15

4/6

0.7258

BMI before pregnancy

21.6 (19.9–24.1)

19.9 (19.1–20.9)

0.0476

BMI at birth

23.8 (22.1–26.2)

23.5 (20.8–24.5)

0.1342

Maternal complications

Diabetes Mellitus, yes/no

7/22

0/10

0.1584

Hypertension, yes/no

2/27

0/10

1.0000

Constipation before pregnancy, yes/no

5/24

4/6

0.1970

Constipation at birth, yes/no/unknown

12/16/1

4/6/0

1.0000

Yogurt dietary habits before pregnancy#, yes/no

12/17

4/6

1.0000

Yogurt dietary habits at Week 36#, yes/no/unknown

18/11/0

3/6/1

0.2493

Natto$ dietary habits before pregnancy#, yes/no

5/24

0/10

0.3019

Natto$ dietary habits at Week 36#, yes/no/unknown

9/18/0

0/9/1

0.0760

Pregnancy course and delivery

Pregnancy weeks at birth, weeks

39.0 (38.0–40.0)

37.5 (36.8–39.3)

0.0540

Delivery, vaginal/cesarean section

16/13

7/3

0.4798

Child weight at birth, grams

2920 (2768–3173)

2950 (2876–3058)

0.7100

Fetal growth restriction, yes/no

3/26

0/10

0.5558

Premature rupture of membranes, yes/no

6/23

2/8

1.0000

Threatened preterm labor, yes/no

1/28

2/8

0.1559

  1. Mothers who delivered twins were excluded.
  2. Data are presented as numbers or median (interquartile range).
  3. p-value was calculated by Fisher’s exact test or Mann–Whitney U test (two-sided).
  4. #Dietary habits were defined as intake occurring 4 times per week or more.
  5. $Natto is a traditional Japanese food of fermented soybeans.