Fig. 5: Target engagement with iExoKrasG12D treatment. | Nature Communications

Fig. 5: Target engagement with iExoKrasG12D treatment.

From: Engineered exosomes with KrasG12D specific siRNA in pancreatic cancer: a phase I study with immunological correlates

Fig. 5: Target engagement with iExoKrasG12D treatment.

A, B Representative images of immunolabeling for pERK, PanCK, αSMA (A), with quantification of percentage of pERK+ panCK+ cancer cells (out of panCK+ cells) and αSMA+ pixels (B) in paired biopsies. This experiment was performed once. C, D Representative images (C), and quantification (D) of CD8+ T cells infiltrates in paired biopsies. Data are presented as mean. Scale bar:100 μm. Source data is provided as Source Data file.

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