Fig. 2: Widespread main effects in the HMDP are consistently identified when concordance rates are sorted by beta value.

The percentage of all HMDP main effect loci with consistent direction of effects in the two sexes was plotted according to the male-derived beta values. Directionality was determined using the sign of the beta value of each main effect locus. Values were graphed by decile according to the absolute value of the beta value. The phenotypes measured included A metabolic traits and B blood traits.