Fig. 6: Late-stage diversifications of bioactive molecules.
From: Pincer-cobalt boosts divergent alkene carbonylation under tandem electro-thermo-catalysis
Reaction conditions: radical precursors (0.4 mmol, 2.0 equiv), Ar‒ZnOPiv (0.6 mmol, 3.0 equiv), alkene (0.2 mmol, 1.0 equiv), CoI2 (10 mol %), bpp (L17, 12 mol %), CO:H2 ( > 90:10, 1 atm), 1,4-dioxane, @ 23 °C, 2 h.
