Fig. 3: Movement behavior of different samples and characterization of their chemotaxis in static and dynamic environments.
From: Size-variable self-feedback nanomotors for glioblastoma therapy via mitochondrial mineralization
Normalized motion trajectories (n = 20 independent samples) and motion speed distribution plots (n = 50 independent samples) of Lip@PAC NPs in (a) bEnd.3 and (b) Gl261 cellular environment (Supplementary Movie 9, 10); Normalized motion trajectories (n = 20 independent samples) and motion speed distribution plots (n = 50 independent samples) of NO-Lip@PAC NMs in (c) bEnd.3 and (d) Gl261 cellular environment (Supplementary Movie 11, 12). e Schematic of the Y-channel model, by Figdraw. f Representative fluorescence images (Scale bar: 1000 μm) and (g) fluorescence quantification of NO-Lip@PAC NMs in Y-channel regions (ii) and (iii) at different times (n = 3 independent samples). h Representative fluorescence images of different samples at the exit of the Ψ-shaped microfluidic channel (Scale bar: 200 μm) and (i) the corresponding fluorescence quantification in the presence of bEnd.3 cellular lysates (n = 3 independent samples). j Representative fluorescence images of different samples at the exit of the Ψ-shaped microfluidic channel (Scale bar: 200 μm) and (k) the corresponding fluorescence quantification in the presence of bEnd.3 and Gl261 cellular lysates (n = 3 independent samples). Data in (g) were presented as mean ± SD. Significance was calculated via a two-tailed unpaired Student’s t test in (g). Source data are provided as a Source Data file.
