Table 3 Reference ranges of echocardiographic parameters according to sex and age

From: Reference values for cardiac dimensions and function in a rural population living in a loiasis-endemic area of the Republic of the Congo: An echocardiographic study

Parameters

Female

Male

< 40 yrs

40–59 yrs

>= 60 yrs

< 40 yrs

40–59 yrs

>= 60 yrs

Reference ranges for left ventricular, aortic and left atrial parameters

LV septal wall thickness, cm

0.5−0.98

0.56−1.06

0.64−1.15

0.54−1.01

0.53−1.11

0.59−1.2

LV diastolic internal diameter, cm

3.62−5.07

3.44−4.96

3.02−4.88

3.75−5.38

3.65−5.33

3.42−5.17

LV diastolic internal diameter indexed to BSA, cm/m²

2.31−3.32

2.16−3.32

2.16−3.36

2.25−3.26

2.18−3.21

2.03−3.26

LV end-diastolic volume (2-chamber), mL

51.28−131.83

49.05−117.43

34.96−94.77

64.84−148.15

58.87−150.9

48.42−136.53

LV end-diastolic volume (4-chamber), mL

48.19−111.9

46.72−105.14

33.08−100

55.98−131.73

56.46−128.71

41.99−136.92

LV end-diastolic volume (mean of the 4- and 2-chambers), mL

53.79−117.81

50.68−108.49

35.67−95.73

63.66−136.69

61.58−135.77

47.95−133.98

LV end-systolic volume (2-chamber), mL

17.1−41.01

11.77−43.74

10.64−34.35

15.48−57.49

16.39−55.91

9.18−58.31

LV end-systolic volume (4-chamber), mL

14.19−44.64

13.82−44.51

9.41−35.47

15.77−56.18

16.98–53.93

11.55−57.17

LV outflow tract area, cm²

2.1−4.15

2.06 − 3.96

2.01−3.52

2.55−4.56

2.61−4.58

2.44−4.52

LV outflow track diameter, cm

1.68−2.3

1.64−2.26

1.62−2.12

1.82−2.42

1.84−2.43

1.79−2.41

LVEF by monoplane Simpson (4-chamber), %

49.32−76.95

44.18−78.48

53.2−78.78

48.4−75.18

48.44−74.91

45.54−77

LVEF (Biplan), %

54.16−76.81

52.28−76.22

55.35−76.02

52.71−75.22

53.1−74.27

45.75−78.12

LV ejection volume (Biplan), mL

32.73−81.96

30.7−73.49

21.02−67.59

40.09−89.61

37.84−89.64

25.63−88.93

Cardiac output, L/min

2.63−7.11

2.66−6.24

1.92−5.76

2.9−6.56

2.56−7.07

2.54−6.45

Aortic sinotubular junction diameter, cm

1.91−2.78

2−3.06

1.89−3.17

1.9−2.97

2.09−3.31

2.31−3.39

Sinus of Valsalva diameter, cm

2.11−3.34

2.2−3.44

2.23−3.59

2.29−3.5

2.45−3.74

2.57−3.82

Ascending aorta diameter, cm

2.15−3.04

2.12−3.43

2.29−3.62

2.08−3.25

2.31−3.62

2.53−3.8

Aortic valve area, cm²

1.53−3.92

1.63−3.46

1.35−3.21

2.11−4.32

2.07−4.31

1.22−5.25

Aortic valve area indexed to BSA, cm²/m²

0.93−2.6

1.06−2.24

0.97−2.24

1.31−2.58

1.24−2.6

0.76−3.25

LA area (2-chamber), cm²

8.98−22

10−21.5

10.35−21.3

11.01−21.9

10.89−23.41

11.56−22.7

LA area (4-chamber), cm²

8.57−19.44

8.25−21.66

8.81−20.21

8.94−21.07

8.45−22.1

9.42−22.31

LA area (4-chamber) indexed to BSA, cm²/m²

5.69−12.42

5.79−13.62

5.98−14.38

5.53−12.6

5.14−13.18

5.51−14.05

LA volume, mL

14.89–62.95

16.27−65.99

23.86−59.06

21.86−63.24

19.8−71.67

23.84−70.3

LA volume indexed to BSA, mL/m²

10.56−39.53

11.48−41.9

15.34−42.97

14.54−37.23

12.27−42.66

14.17−43.89

Reference ranges for right ventricular, vena cava, pulmonary valve and right atrial parameters

RV basal diameter, cm

2.48−4.54

2.67−4.62

2.95−4.28

2.82−4.86

2.95−4.81

2.85 − 5.12

RV longitudinal diameter,  cm

2.34−3.71

2.36−3.77

2.36−3.86

2.33−3.87

2.57−4

2.64 − 3.86

RVOT prox, cm

2.28−3.62

2.45−3.76

2.33−3.76

2.42−3.78

2.49−3.91

2.54 − 3.93

RV end-diastolic area, cm²

8.2−17.11

7.67−17.66

7.7−16.31

9.4−21.22

9.28−20.48

8.75 − 19.83

RV end-systolic area, cm²

3.72−10.06

3.89−9.41

3.68−8.06

4.57−11.82

4.33−11.85

4.45 − 11.27

RA area, cm²

7.88−17.41

7.54−18.83

7.34−16.37

8.43−19.89

8.65−19.7

8.29 − 21.99

TAPSE, cm

1.87−3.23

1.77−3.38

1.73−2.73

1.76−3.35

1.77−3.2

1.6 − 3.25

IVC max diameter, mm

8.6−20.92

6.7−23.02

6.11−21.06

9.14−23.99

8.74−25.28

6.38 − 21.48

IVC min diameter, mm

1.9−13.82

1.43−14.8

0.97−11.55

2.57−18.05

2.37−17.49

1.33 − 14.03

IVC collapsibility index, %

(−0.33−2.46)

(−0.44−2.55)

(−6.43−10.63)

(−1.06−2.7)

(−0.46−2.23)

(−1.87 − 4.26)

IVC collapse percentage, %

18.22−76.06

15.13−77.36

20.76−84.61

5.83 − 71.56

11.17 − 72.87

10.72 − 78.46

Reference ranges for doppler parameters

Aortic valve peak velocity, cm/s

85.26−169.62

96.52−166.37

88.54−170.55

88.67−154.32

85.47−158.34

72.04−160.83

Mean aortic valve gradient, mmHg

1.49−6.69

1.79−6.5

1.69−5.98

1.65−5.48

1.47−5.73

1.28−5.51

Pulmonary artery pulsatility index

0.62−1.04

0.6−1.04

0.59−1.02

0.67−1.11

0.63−1.06

0.59−1.13

Pulmonary valve acceleration time, s

0.09−0.19

0.08−0.19

0.06−0.19

0.09−0.19

0.08–0.2

0.05−0.19

Peak TR velocity, cm/s¥

148.13−269.81

140.69−292.71

175.24−288.54

130.22 − 286.8

149.16−285.38

167.03−293.9

Peak TR gradient, mmHg¥

8.13−27.52

7.69−31.22

11.47−32.19

6.41−29.61

9.23−29.46

10.5−32.75

Peak S velocity TR, cm/s

10.02−17.13

9.38−16.94

8.41−15.19

9.41−16.93

9.42−16.31

8.44−17.18

Peak mitral inflow A velocity, cm/s

27.85−83.04

35.17−103.31

46.43−99.36

26.37−72.48

31.64−84.32

32.07−102.07

Peak mitral inflow E velocity, cm/s

48.7−123.78

44.91−114.16

38.63−90.72

48.14−117.5

44.23−103.48

30.15−102.89

E-wave deceleration slope, cm/s²

62.27−1052.18

148.76−779.13

120.88−551.21

125.83 −837.39

97.91−714.14

33.06−655.33

E-wave deceleration time, s

0.06–0.27

0.09−0.25

0.12−0.25

0.09−0.27

0.1−0.28

0.09−0.3

Lateral e’ velocity, cm/s

11.65−20.95

6.69−17.68

5.79−14.04

10.38−22.21

8.57−18.49

4.1−16.7

Septal e’ velocity, cm/s

5.27−18.15

5.07−12.73

3.96−10.25

6.81−14.98

5.85−12.54

3.83−11.81

E/A

0.64−2.57

0.32−2.12

0.49−1.33

0.74−2.77

0.67−1.97

0.4−1.66

Average e’ velocity, cm/s

9.31−18.7

5.89−15.03

5.45−11.57

9.29−17.9

7.63−15.03

4.25−13.96

E/e’ ratio (septal)

3.42−11.88

4.94–13.25

4.15−14.93

3.83−11.77

3.73−12.86

4.21−13.09

E/e’ ratio (lateral)

2.87−7.84

3.7−9.65

2.5−11.14

2.55−7.87

2.56−8.73

2.26−11.1

E/e’ ratio (average)

3.39−9.61

4.71−10.96

3.73−12.63

3.41−9.6

3.41−10.52

3.55−11.78

  1. ¥This parameter was specifically assessed in participants with TR, leading to the exclusion of 95 participants without this condition from the calculation. AR Aortic Regurgitation, BSA Body Surface Area, IVC Inferior Vena Cava, LA Left Atrium/Left Atrial, LV Left Ventricle/Left Ventricular, LVEF Left Ventricular Ejection Fraction, RA Right Atrium/Right Atrial, RV Right Ventricle/Right Ventricular, RVOT prox: Proximal RV Outflow Tract Diameter, TAPSE Tricuspid Annular Plane Systolic Excursion, TR Tricuspid Regurgitation, VTI Velocity Time Integral.