Table 3 Reference ranges of echocardiographic parameters according to sex and age
Parameters | Female | Male | ||||
|---|---|---|---|---|---|---|
< 40 yrs | 40–59 yrs | >= 60 yrs | < 40 yrs | 40–59 yrs | >= 60 yrs | |
Reference ranges for left ventricular, aortic and left atrial parameters | ||||||
LV septal wall thickness, cm | 0.5−0.98 | 0.56−1.06 | 0.64−1.15 | 0.54−1.01 | 0.53−1.11 | 0.59−1.2 |
LV diastolic internal diameter, cm | 3.62−5.07 | 3.44−4.96 | 3.02−4.88 | 3.75−5.38 | 3.65−5.33 | 3.42−5.17 |
LV diastolic internal diameter indexed to BSA, cm/m² | 2.31−3.32 | 2.16−3.32 | 2.16−3.36 | 2.25−3.26 | 2.18−3.21 | 2.03−3.26 |
LV end-diastolic volume (2-chamber), mL | 51.28−131.83 | 49.05−117.43 | 34.96−94.77 | 64.84−148.15 | 58.87−150.9 | 48.42−136.53 |
LV end-diastolic volume (4-chamber), mL | 48.19−111.9 | 46.72−105.14 | 33.08−100 | 55.98−131.73 | 56.46−128.71 | 41.99−136.92 |
LV end-diastolic volume (mean of the 4- and 2-chambers), mL | 53.79−117.81 | 50.68−108.49 | 35.67−95.73 | 63.66−136.69 | 61.58−135.77 | 47.95−133.98 |
LV end-systolic volume (2-chamber), mL | 17.1−41.01 | 11.77−43.74 | 10.64−34.35 | 15.48−57.49 | 16.39−55.91 | 9.18−58.31 |
LV end-systolic volume (4-chamber), mL | 14.19−44.64 | 13.82−44.51 | 9.41−35.47 | 15.77−56.18 | 16.98–53.93 | 11.55−57.17 |
LV outflow tract area, cm² | 2.1−4.15 | 2.06 − 3.96 | 2.01−3.52 | 2.55−4.56 | 2.61−4.58 | 2.44−4.52 |
LV outflow track diameter, cm | 1.68−2.3 | 1.64−2.26 | 1.62−2.12 | 1.82−2.42 | 1.84−2.43 | 1.79−2.41 |
LVEF by monoplane Simpson (4-chamber), % | 49.32−76.95 | 44.18−78.48 | 53.2−78.78 | 48.4−75.18 | 48.44−74.91 | 45.54−77 |
LVEF (Biplan), % | 54.16−76.81 | 52.28−76.22 | 55.35−76.02 | 52.71−75.22 | 53.1−74.27 | 45.75−78.12 |
LV ejection volume (Biplan), mL | 32.73−81.96 | 30.7−73.49 | 21.02−67.59 | 40.09−89.61 | 37.84−89.64 | 25.63−88.93 |
Cardiac output, L/min | 2.63−7.11 | 2.66−6.24 | 1.92−5.76 | 2.9−6.56 | 2.56−7.07 | 2.54−6.45 |
Aortic sinotubular junction diameter, cm | 1.91−2.78 | 2−3.06 | 1.89−3.17 | 1.9−2.97 | 2.09−3.31 | 2.31−3.39 |
Sinus of Valsalva diameter, cm | 2.11−3.34 | 2.2−3.44 | 2.23−3.59 | 2.29−3.5 | 2.45−3.74 | 2.57−3.82 |
Ascending aorta diameter, cm | 2.15−3.04 | 2.12−3.43 | 2.29−3.62 | 2.08−3.25 | 2.31−3.62 | 2.53−3.8 |
Aortic valve area, cm² | 1.53−3.92 | 1.63−3.46 | 1.35−3.21 | 2.11−4.32 | 2.07−4.31 | 1.22−5.25 |
Aortic valve area indexed to BSA, cm²/m² | 0.93−2.6 | 1.06−2.24 | 0.97−2.24 | 1.31−2.58 | 1.24−2.6 | 0.76−3.25 |
LA area (2-chamber), cm² | 8.98−22 | 10−21.5 | 10.35−21.3 | 11.01−21.9 | 10.89−23.41 | 11.56−22.7 |
LA area (4-chamber), cm² | 8.57−19.44 | 8.25−21.66 | 8.81−20.21 | 8.94−21.07 | 8.45−22.1 | 9.42−22.31 |
LA area (4-chamber) indexed to BSA, cm²/m² | 5.69−12.42 | 5.79−13.62 | 5.98−14.38 | 5.53−12.6 | 5.14−13.18 | 5.51−14.05 |
LA volume, mL | 14.89–62.95 | 16.27−65.99 | 23.86−59.06 | 21.86−63.24 | 19.8−71.67 | 23.84−70.3 |
LA volume indexed to BSA, mL/m² | 10.56−39.53 | 11.48−41.9 | 15.34−42.97 | 14.54−37.23 | 12.27−42.66 | 14.17−43.89 |
Reference ranges for right ventricular, vena cava, pulmonary valve and right atrial parameters | ||||||
RV basal diameter, cm | 2.48−4.54 | 2.67−4.62 | 2.95−4.28 | 2.82−4.86 | 2.95−4.81 | 2.85 − 5.12 |
RV longitudinal diameter, cm | 2.34−3.71 | 2.36−3.77 | 2.36−3.86 | 2.33−3.87 | 2.57−4 | 2.64 − 3.86 |
RVOT prox, cm | 2.28−3.62 | 2.45−3.76 | 2.33−3.76 | 2.42−3.78 | 2.49−3.91 | 2.54 − 3.93 |
RV end-diastolic area, cm² | 8.2−17.11 | 7.67−17.66 | 7.7−16.31 | 9.4−21.22 | 9.28−20.48 | 8.75 − 19.83 |
RV end-systolic area, cm² | 3.72−10.06 | 3.89−9.41 | 3.68−8.06 | 4.57−11.82 | 4.33−11.85 | 4.45 − 11.27 |
RA area, cm² | 7.88−17.41 | 7.54−18.83 | 7.34−16.37 | 8.43−19.89 | 8.65−19.7 | 8.29 − 21.99 |
TAPSE, cm | 1.87−3.23 | 1.77−3.38 | 1.73−2.73 | 1.76−3.35 | 1.77−3.2 | 1.6 − 3.25 |
IVC max diameter, mm | 8.6−20.92 | 6.7−23.02 | 6.11−21.06 | 9.14−23.99 | 8.74−25.28 | 6.38 − 21.48 |
IVC min diameter, mm | 1.9−13.82 | 1.43−14.8 | 0.97−11.55 | 2.57−18.05 | 2.37−17.49 | 1.33 − 14.03 |
IVC collapsibility index, % | (−0.33−2.46) | (−0.44−2.55) | (−6.43−10.63) | (−1.06−2.7) | (−0.46−2.23) | (−1.87 − 4.26) |
IVC collapse percentage, % | 18.22−76.06 | 15.13−77.36 | 20.76−84.61 | 5.83 − 71.56 | 11.17 − 72.87 | 10.72 − 78.46 |
Reference ranges for doppler parameters | ||||||
Aortic valve peak velocity, cm/s | 85.26−169.62 | 96.52−166.37 | 88.54−170.55 | 88.67−154.32 | 85.47−158.34 | 72.04−160.83 |
Mean aortic valve gradient, mmHg | 1.49−6.69 | 1.79−6.5 | 1.69−5.98 | 1.65−5.48 | 1.47−5.73 | 1.28−5.51 |
Pulmonary artery pulsatility index | 0.62−1.04 | 0.6−1.04 | 0.59−1.02 | 0.67−1.11 | 0.63−1.06 | 0.59−1.13 |
Pulmonary valve acceleration time, s | 0.09−0.19 | 0.08−0.19 | 0.06−0.19 | 0.09−0.19 | 0.08–0.2 | 0.05−0.19 |
Peak TR velocity, cm/s¥ | 148.13−269.81 | 140.69−292.71 | 175.24−288.54 | 130.22 − 286.8 | 149.16−285.38 | 167.03−293.9 |
Peak TR gradient, mmHg¥ | 8.13−27.52 | 7.69−31.22 | 11.47−32.19 | 6.41−29.61 | 9.23−29.46 | 10.5−32.75 |
Peak S velocity TR, cm/s | 10.02−17.13 | 9.38−16.94 | 8.41−15.19 | 9.41−16.93 | 9.42−16.31 | 8.44−17.18 |
Peak mitral inflow A velocity, cm/s | 27.85−83.04 | 35.17−103.31 | 46.43−99.36 | 26.37−72.48 | 31.64−84.32 | 32.07−102.07 |
Peak mitral inflow E velocity, cm/s | 48.7−123.78 | 44.91−114.16 | 38.63−90.72 | 48.14−117.5 | 44.23−103.48 | 30.15−102.89 |
E-wave deceleration slope, cm/s² | 62.27−1052.18 | 148.76−779.13 | 120.88−551.21 | 125.83 −837.39 | 97.91−714.14 | 33.06−655.33 |
E-wave deceleration time, s | 0.06–0.27 | 0.09−0.25 | 0.12−0.25 | 0.09−0.27 | 0.1−0.28 | 0.09−0.3 |
Lateral e’ velocity, cm/s | 11.65−20.95 | 6.69−17.68 | 5.79−14.04 | 10.38−22.21 | 8.57−18.49 | 4.1−16.7 |
Septal e’ velocity, cm/s | 5.27−18.15 | 5.07−12.73 | 3.96−10.25 | 6.81−14.98 | 5.85−12.54 | 3.83−11.81 |
E/A | 0.64−2.57 | 0.32−2.12 | 0.49−1.33 | 0.74−2.77 | 0.67−1.97 | 0.4−1.66 |
Average e’ velocity, cm/s | 9.31−18.7 | 5.89−15.03 | 5.45−11.57 | 9.29−17.9 | 7.63−15.03 | 4.25−13.96 |
E/e’ ratio (septal) | 3.42−11.88 | 4.94–13.25 | 4.15−14.93 | 3.83−11.77 | 3.73−12.86 | 4.21−13.09 |
E/e’ ratio (lateral) | 2.87−7.84 | 3.7−9.65 | 2.5−11.14 | 2.55−7.87 | 2.56−8.73 | 2.26−11.1 |
E/e’ ratio (average) | 3.39−9.61 | 4.71−10.96 | 3.73−12.63 | 3.41−9.6 | 3.41−10.52 | 3.55−11.78 |