Fig. 3: Core genome and overall sequence variation of blaKPC-2-positive IncU and blaNDM-1-positive IncN plasmids. | Nature Communications

Fig. 3: Core genome and overall sequence variation of blaKPC-2-positive IncU and blaNDM-1-positive IncN plasmids.

From: Plasmid dynamics driving carbapenemase gene dissemination in healthcare environments: a nationwide analysis of closed Enterobacterales genomes

Fig. 3

A Comparison of the core genome of PC1, the predominant blaKPC-2-positive IncU plasmid type, with all other blaKPC-2-positive IncU plasmids. B Comparison of the core genome of PC2, the predominant blaNDM-1-positive IncN plasmid type, with all other blaNDM-1-positive IncN plasmids. Visualization of structural differences between representative sequences of C PC1 and other closely-related blaKPC-2-positive IncU plasmids, as marked by the red box in this figure (A), and D PC2 and other closely-related blaNDM-1-positive IncN plasmids, as marked by the red box in this figure (B). In the linear alignments generated by Clinker, similar colors indicate conserved regions; grey arrows represent inserted genes.

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