Fig. 4: Phylogeny and gene complement of blaKPC-2-positive IncU and blaNDM-1-positive IncN plasmids.

A Matrix depicting the gene complement of PC1, the predominant blaKPC-2-positive IncU plasmid type, and the closely similar plasmids PC7 and PC43. Plasmids are ordered along the y-axis according to the k-mer similarity dendrogram shown on the left. Genes are ordered along the x-axis, and those of interest are annotated. B Matrix depicting the gene complement of PC2, the predominant blaNDM-1-positive IncN plasmid type, and the closely similar plasmids PC20 and PC49. Representative closed plasmids are shown and annotated.