Fig. 5: Association of specific cell clusters with low DIPs LAIV-induced innate immune responses. | Nature Communications

Fig. 5: Association of specific cell clusters with low DIPs LAIV-induced innate immune responses.

From: Live attenuated influenza vaccine with low proportions of defective interfering particles elicits robust immunogenicity and cross-protection

Fig. 5: Association of specific cell clusters with low DIPs LAIV-induced innate immune responses.

a Ratios of the proportion of LAIV-inoculated cell cluster to that of the placebo. b Violin plots of normalized certain gene expressions in goblet cells. Group differences were assessed using the Wilcoxon rank-sum test, with p-values adjusted for multiple comparisons via the Benjamini‒Hochberg method. c Dot plots of the GOBP terms in goblet cells of the low DIPs LAIV inoculation group. Gene Set Enrichment Analysis method was used with p-values adjusted for multiple comparisons via the Benjamini‒Hochberg method. P < 0.05 were considered significant and are outlined in black circles.

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